Steroid Hormone Pathways by Genova

Detailed steroid hormone pathway chart from Precision Analytical and Nourish Medical Center. Understand how your body produces cortisol, DHEA, and sex hormones.

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Steroid Hormone Pathways by Genova

Steroid hormones—including cortisol, DHEA, testosterone, estrogen, and progesterone—are all produced from the same starting material (cholesterol) through interconnected pathways. This detailed chart from Genova Diagnostics illustrates these pathways and helps you understand your hormone test results.

At Nourish Medical Center, we use comprehensive hormone testing — including serum (blood), urine, and/or salivary panels — to evaluate hormone levels, metabolism, and overall endocrine balance. This pathway chart helps you interpret your results and understand how different hormones relate to each other.

You’ll Learn:
• The complete steroid hormone production pathway
• How stress affects sex hormone production
• Where metabolic blocks or imbalances may occur

This handout includes the comprehensive steroid hormone pathway diagram used by Genova Diagnostics, showing the conversion of cholesterol to pregnenolone, the “pregnenolone steal” that occurs under chronic stress, and all the downstream hormones produced. You’ll understand why high cortisol can lead to low sex hormones and how to interpret your hormone test results with your Nourish doctor.

Who This Handout Is For:
Patients who have completed DUTCH or Genova hormone testing
Individuals with adrenal fatigue or chronic stress
Anyone with sex hormone imbalances
Those wanting to understand their hormone metabolism

Download this handout to help understand your steroid hormone pathways and test results.